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Semaglutide 2.4 mg (Wegovy) has shown robust weight loss in primary obesity trials, with mean weight reductions of 14.9% in the STEP 1 trial published in the New England Journal of Medicine (2021)

Petrof EO, Gloor GB, Vanner SJ, Weese SJ, Carter D, Daigneault MC

European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task ForceSecond revision

Apart from side effects which seem to be minor, mainly involving nausea there are a few other downsides of semaglutide

These peptides are not magic, but they can be a strong support tool for people who are already doing the work and want something extra behind their progress

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