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Disruptions to Core Clock Genes (Basic Science) Disruptions to core circadian clock proteins, specifically Bmal1 , has also resulted in increased reactive oxygen species, which is critical during mediation/exacerbation of damage during reperfusion in ischemia (Peek et al., 2017)

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Fodor A, Tiperciuc B, Login C, Orasan OH, Lazar AL, Buchman C et al

This occurs when there is an imbalance between free radicals (unstable molecules) and antioxidants

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BPC-157: While BPC-157 primarily acts through the modulation of nitric oxide and the promotion of angiogenesis, GHK-Cu operates at the level of gene expression and the extracellular matrix