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Also, every tobacco that is manufactured for smoking including the one that goes into pipes is treated with pesticides and other chemicals so a lot of those that are present in cigarettes are present in pipe tobacco

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Tobacco smoke has been shown to inhibit CYP2A6, leading to a decrease or at least a slowdown in nicotine metabolism in smokers compared to non-smokers (Lee et al., 1987

Long-term health effects on users and bystanders are still unknown

Smoking a cigarette yields 0.5-2.0 mg of nicotine to the smoker but eating the cigarette (or other nicotine product) is a whole different ballgame as all of the nicotine becomes available for absorption into the body

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