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Dual Action on Receptors Amylin Receptor Activation: When cagrilintide binds to the amylin receptor, it enhances the natural satiety signals that help reduce food intake
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11 CuiH
In a healthy liver, hepatic lipid metabolism maintains intracellular lipid equilibrium, while controlled lipid oxidation supports hepatic energy metabolism, sustaining normal liver function [314]
3.1.2 Anti-inflammatory and immunomodulatory effects Chronic hepatic inflammation, driven by activated Kupffer cells, infiltrating macrophages, and pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF- ) and interleukin-6 (IL-6), is a crucial factor in MASLD progression to steatohepatitis and fibrosis
NICE guidance emphasises individualised treatment decisions, balancing therapeutic benefit against tolerability and patient preference
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