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The starting dose exists for tolerability, not efficacy

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Physiological requirement of a healthy 70-kg adult for taurine may be 75 mg/day or 1.07 mg/kg BW per day based on its urinary excretion of 72 mg/day (Laidlaw et al

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Methods Study approval All the related experiments and protocols used in these studies were approved by the Ethical Committees of the University of Cordoba and Junta de Andalusia (Spain), according to EU normative for the use and care of experimental animals (EU Directive 2010/63/UE, September 2010)