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Rats can be exposed to a wide range of oxidative stress-inducing agents such as ethanol, d-galactose (d-gal), iron, alloxan (ALX), streptozotocin (STZ), carbon tetrachloride (CCl), bromobenzene, radiation, noise, methylmercuric chloride (MeHgCl), tert-butyl hydroperoxide (t-BOOH), and hydrogen peroxide (HO)

The results showed a significant increase in blood GSH levels and a decrease in oxidative stress, as indicated by the reduction of 8-OHdG (a marker of oxidative DNA damage)

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The index of bioavailability (F) was calculated using the AUC data obtained in an intravenous pharmacokinetics study with the same test article (RBM Exp