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Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS

Cancer cells use precursors derived from the TCA cycle intermediates to synthesize proteins, lipids, and nucleic acids

The molecular weight of PT-141 (1,025 Da) falls well within the optimal range for nasal delivery

It is not medical advice, dosing guidance, or a recommendation for human use

Lifestyle: not a smoker, no alcohol and no excessive processed food that causes glutathione depletion

As illustrated in GSE17737, mice received nose-only exposure to 4% mainstream cigarette smoke or air for 2 h/day, 5 days/week over 12 weeks