And if youre already depleted from age, stress, toxins, or illness food alone usually isnt enough to catch up
(PubMed) Carr AC, Cook J
Pain at the injection site was extremely common and was reported in over 85% of recipients, irrespective of the dose
A 2019 review in Nutrients examining NAD+ precursor safety in human clinical trials found oral NMN and NR well-tolerated at doses up to 1,000 mg/day with no serious adverse events reported
Here are some early warning signs that you may have a mild to moderate deficiency: 5 Lack of energy Joint and muscle aches and pains Foggy brain Low immunity Poor sleep These are the symptoms of a severe insufficiency: 6 Anemia (low levels of iron) Metabolic acidosis (build-up of too much acid in the body) Frequent infections Seizures, Alzheimers disease, Parkinsons disease Loss of coordination (Ataxia) Liver disease Heart attack and stroke 7 If you feel like you have a deficiency, I recommend increasing supplemental glutathione levels using the methods I outline below
The fact is that GP audits (and no clinical evidence or patient involvement of any kind) eventually made three monthly injections the optimal maintenance dose of B12
