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Pouya Shafipour, a family and obesity medicine physician for Providence Saint Johns Health Center in California, told Medical News Today that anyone considering taking semaglutides should do so in close consultation with a doctor

Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide) are FDA-approved for chronic weight management in adults with a BMI 30 kg/m, or 27 kg/m with at least one weight-related comorbidity

Initially utilized as a diabetes treatment, this injectable drug has emerged as a breakthrough in chronic weight management

LSECs make up around 3% of liver cell volume, and in mice that did not have LSEC receptors, there were no benefits to taking semaglutide (even after losing 20% of their body weight)