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Mutating this residue to an alanine shows a similar increase in carnitine K M as the mutants above (Fig

FOXO3a itself induces a set of atrophy-related genes, specifically the muscle-specific ubiquitin ligases, MAFbx and MuRF-1, which promote the breakdown of the myofibrillar apparatus [17]

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Neurotrophic factors are associated with the pathogenesis of depression (87, 88)

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