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Description

Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid

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Far-UV spectra were collected in the range of 180260 nm with a step size of 1 nm and at least 20 accumulations for 0.5 s per wavelength

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The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool

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