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These are fundamentally different molecules with different receptor profiles

M., Moroan, E., Dumitrescu, D.-E., Roca, A

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Constipation On the opposite end, constipation affected 24.2% of semaglutide 2.4 mg users versus 11.1% on placebo in the STEP trials

GLP-1 medications such as semaglutide and tirzepatide directly reduce hunger, slow stomach emptying, and help you feel full longer, which can significantly cut cravings