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This is why weekly dosing works: the old dose is still partially active when you inject the new one, creating a steady therapeutic window

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5B, lane 13), as well as COP1-c-Jun with DET1-Ube2e2 complexes (with or without DDB1-DDA1 and either neddylated or non-neddylated CULLIN4-RBX1), did not catalyze c-Jun ubiquitination (Fig

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Acknowledgments We acknowledge the traditional custodians of the lands this project was conducted on, the Wurundjeri people of the Kulin nation, Professor Freya Fowkes (Burnet Institute) for assisting with statistical analysis, Dr Philippe Boeuf (Burnet Institute) and Professor Christian Doerig (RMIT) for helpful discussions and feedback on the manuscript, Professor Patrick Humbert (La Trobe University) for providing access to flow cytometry equipment, and The Australian Red Cross Blood Bank for the supply of human erythrocytes

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Acta Physiol (Oxf) (2020) 229:e13464

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The symptoms of gastroparesis can significantly impair ones quality of life, ranging from mild discomfort to debilitating pain

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Neuropsychiatric effects of antimicrobial agents

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