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1 West Beichen Road, Chaoyang, Beijing 100101, Peoples Republic of China e-mail: [email protected] This article was submitted to Plant Physiology, a specialty of Frontiers in Plant Science
Bjrbaek and A
Some of the second-generation antipsychotic drugs cause increased weight gain and increased lipid levels compared to some first-generation drugs, and a small percentage of patients develop diabetes mellitus, most often seen with clozapine and olanzapine (2)
Therefore, considering the overlapping yet distinct roles of insulin and IGF-1 in the brain, disruptions in their signaling pathways due to IR may contribute to the neurobiological mechanisms underlying depression in individuals with T2DM
A First-of-Its-Kind Approval The FDA approved the oral Wegovy pill on December 22, 2025 , formally clearing it for obesity and long-term weight management
