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Maintenance phase: settle at the lowest dose that delivers the desired effect

Efectos secundarios : Nuseas, diarrea, disminucin del apetito, vmitos y dolor abdominal

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Time since T2D diagnosis was longer in the CKD group

Transcription factors such as nuclear factor erythroid related factor (Nrf2), nuclear factor kappa B (NF-kB), and AP-1 were reported to be activated by antioxidants such as curcumin, resveratrol, and quercetin (Wong et al., 2018)