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However, it is crucial to evaluate the long-term safety of these nutrients, as extensive research indicates that nutrient supplementation can pose risks, including gastrointestinal distress, an increased incidence of bleeding, and a heightened prevalence of cancer and certain diseases, particularly in immunocompromised individuals and smokers

Dimakakos PB, Stefanopoulos T, Antoniades P, Antoniou A, Gouliamos A, Rizos D

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It requires larger injection volumes, which some users actually prefer because drawing a bigger volume is easier to measure accurately on a standard syringe