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The repeated subcutaneous injection of these peptides for 21 days significantly decreased body weight and significantly changed their body weight reduction ratio (semaglutide, 19.7 4.1%

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Detection of GEP44 in Y1-R, Y2-R, and GLP-1R-expressing cells in caudal brainstem nuclei associated with appetite control (AP/NTS) To visualize GEP44 localization in the brain, we injected rats with fluorescently labeled (f)-Cy5-GEP44 either intraperitoneally (IP