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Nature 395 , 763770 (1998)

Frequent vomiting can lead to dehydration, which, as mentioned earlier, can make blood thicker and put more strain on veins

Use with caution to the patient who is having adrenal insufficiency, autonomic neuropathy and receiving beta-adrenergic blocking agent Vitamin B12 deficiency Prolonged use of metformin can interfere in the absorption of vitamin b12 in the stomach

It is available only as a compounded preparation through 503A/503B pharmacies

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