The GP would prescribe the correct amount for you, so it would be hard to overdose. But if too much vitamin B12 is taken, certain symptoms may arise - including a change to your pee
Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms
it is produced by traditional organic synthesis and supplied as a crystalline solid for laboratory reconstitution in a research-appropriate solvent
The weight maintenance after tirzepatide guide addresses the related question of sustaining results during and after the transition off active treatment
A vitamin B12 deficiency may be the cause
Image 1: Cellular metabolism of various forms of vitamin B12 Image: Simplified depiction of the metabolism of various forms of vitamin B12 supplements in the cytosol