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In the gutbrain axis specifically, short-chain fatty acids (SCFAs), butyrate, acetate, and propionate, produced from gut microbiota fermentation of nondigestible fiber, improve both energy and glucose homeostasis in rodent models of obesity and insulin resistance 278,279

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10.1007/s00125-016-3874-y Diabetologia 19 GautronL.ElmquistJ

Therefore, its vital for employers to be more strategic about offering holistic weight management resources that bring together a cross-functional team of primary care providers, pharmacists, care managers and more to support their population while also controlling spend

Ozempic, which is only FDA-approved to treat diabetes, does not come with that warning

Semaglutide crosses the blood-brain barrier and acts on appetite centers in the hypothalamus and brainstem