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The main driver is loss of facial fat, especially when weight is lost rapidly

Statements Author contributions NC: Writing original draft, Conceptualization, Data curation, Visualization

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It is endogenously distributed across both central and peripheral tissues, including the hypothalamus, pituitary gland, and limbic system, making it a broadly studied subject in neuroendocrine and sleep biology research

In contrast, when exogenous iron was administered, these animals developed knee osteoarthritis (157)

Why Can GLP-1 RAs Cause Nutritional Deficiencies