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Appetite and Digestive Adjustments : As your body adapts to Tirzepatide, you may notice changes in your appetite and digestive patterns

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Relative contraindications requiring careful consideration and enhanced medical supervision include history of pancreatitis, severe gastrointestinal disease including gastroparesis, diabetic retinopathy (requires ophthalmologic monitoring during therapy), severe kidney disease, history of suicidal ideation or severe depression, gallbladder disease or history of cholecystitis, and age under 18 years

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If you miss multiple doses, your clinician may recommend restarting at a lower step to reduce side effects