High-throughput methods for combinatorial drug discovery
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[DOI] [PMC free article] [PubMed] [Google Scholar] Santos L, Benitez-Rosendo A, Bresque M, Camacho-Pereira J, Calliari A, Escande C
For example, the treatment with acetyl-l-carnitine induced haeme oxygenase enzyme in rat astrocytes in a dose- and time-dependent fashion, heat shock protein 60 upregulation, and increased expression of the nuclear factor erythroid 2-related factor 2 transcription factor, a master regulator of antioxidant proteins [18]
Other elements to this equation are the cost of medication, side-effects, accessibility, and availability of drugs
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