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If a person's genes could help clinicians identify the best drug from the outset, it could change how these treatments are prescribed

Meta-analysis resulted in a standardised mean difference (SMD) of -0.18 (95%CI -0.46-0.10) across 199 cases and 185 controls using a random effects model

a subcutaneous injection is the alternative in rodent research

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Mechanistically, these agents activate the Nrf2/ARE, NF-B, MAPK, PI3K/Akt/mTOR, and SIRT1/PGC-1 pathways, protect mitochondria and the bloodnerve barrier, and upregulate endogenous antioxidant enzymes

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