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Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice

[98] Gaykema, R.P., Newmyer, B.A., Ottolini, M., Raje, V., Warthen, D.M., Lambeth, P.S., et al.2017

Mice homozygous for the spontaneous ( Lepr db ) mutation develop severe obesity starting at 34 weeks of age, accompanied by overnutrition-related complications including postprandial hyperglycemia, and eventually pancreatic cell atrophy and hypoinsulinemia

Anti-diabetic effect of a traditional Chinese medicine formula

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