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Additionally, L-arginine acts as a precursor to other amino acids, including glutamate, proline, and creatine, and is essential for the health and functioning of your immune system

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A recent proteomic study suggested altered mitochondrial function in the cerebrovasculature isolated from deceased cognitively healthy E4 carriers compared to non-E4 carriers, indicating that cerebrovascular bioenergetics may indeed be altered in cognitively healthy E4 carriers (Ojo et al., 2021)

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