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Only two mutations affecting splicing have been discovered thus far

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While they are generally safe to use, they can cause side effects, such as nausea, vomiting, and diarrhea

And I dont think thats because cholesterol causes heart disease, but I think its because its a reflection of your overall metabolism being more slow in terms of actually using up the cholesterol

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This meta-analysis indicates that GLP-1 receptor agonists are safe and effective in modestly reducing weight, BMI, glycated hemoglobin A1c, and systolic blood pressure in children and adolescents with obesity in a clinical setting, albeit with increased rates of nausea [17]