Although the role of adipocyte-derived MTs is not fully understood, it is speculated that these stress-response and metal-binding proteins may act as antioxidants, shielding fatty acids from oxidative harm in adipocytes and during their transit from the micro-vasculature [18]
[37] Sadeghi A, Saedisomeolia A, Jalili-Baleh L, et al
In a retrospective study, Lyons et al., evaluated the effects of semaglutide in 30 obese patients with HS, reporting reductions in weight, BMI, and metabolic markers such as HbA1c, along with improvements in DLQI and a decreased frequency of flares [160]
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