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For instance, the narrow therapeutic index of colchicine necessitates cautious dosing to prevent toxicity, while uricase therapies (e.g., pegloticase) are challenged by immunogenicity and instability (Yang Y

Oxidative stress has been linked to various pregnancy complications, including gestational diabetes, preeclampsia, and fetal growth restrictions

Bazzano A, Zeldin A, Schuster E, Barrett C, Lehrer D

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Brueggeman et al., 2022), severely affected by SARS-CoV-2 viral infection (Polonikov, 2020

The two delivery routes have different pharmacokinetic profiles in published research