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10.1002/term.2431 32 ChenL.HeX.ZhangY.ChenX.LaiX.ShaoJ.et al (2014a)

By reinforcing this barrier, it prevents the translocation of luminal antigens and endotoxins into the bloodstream, a key pathological driver in many chronic inflammatory and autoimmune conditions

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Additionally, four genes, plus one continuous gene deletion, are associated with peripheral neuropathy, a mechanism of potential importance to CVS (4, 6), and thus also were also elevated to Possibly related status (Table 5, genes in yellow font)

Hence the reason the peptide was marketed as the Barbie peptide with its binding ability to MCR1