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The idea is "tobacco harm reduction"switching from a very high-risk product to a (theoretically) significantly lower-risk one

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so, does the amount of nicotine consumed in each puff

I realize I will need to either talk to my friends about not smoking around me for a period of time or I will reduce the amount of time I spend with them and I will meet them in places where it is not possible to smoke

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All quantitations corrected for variations in the instrument response using IS-normalized relative response factors defined as [analyte response]/[analyte mass injected]/([IS response]/[IS mass injected])