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Raimondi S, Sera F, Gandini S, Iodice S, Caini S, Maisonneuve P, et al

As we learn more about GLP-1 RAs, we realize that they target many organ systems, including the pancreas, the stomach, brain, heart, kidneys, immune system (due to reduced inflammation), and skeletal muscle

Notably, these inhibitory effects were attenuated in alcohol-exposed rats, suggesting that substance use may blunt GLP-1R responsiveness in relapse-relevant circuits

The result is noticeable, sometimes alarming, diffuse hair loss

To avoid this, scientists recommend not consuming more than the suggested maximum single dose of allulose of 0.4 g per kg of body weight, or the maximum total daily intake of 0.9 g per kg of body weight, doses at which no significant side effects were reported besides loose stool