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Thus, it reduces the insulin dose requirement, and also attenuates the weight gain associated with insulin therapy

GLP-1RAs augment the mitophagy pathway to suppress NLRP3 inflammasome and ameliorate oxidative stress-induced injury in the liver [140]

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The expression of its main receptor, TLR5, is also markedly upregulated

Proc Natl Acad Sci U S A 97: 6874-6879, 2000