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Canto C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y,

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I., Acosta, A., Faubion, S., Shufelt, C., & Hurtado Andrade, M

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however, loss of sygl-1 results in a progenitor zone about half the size as that found in wild-type animals ( sygl-1 mutants corresponds to the region where LST-1 is expressed, suggesting that SYGL-1 expression sets up the GSC pool size, and in its absence LST-1 determines the pool size ( fbf-1 fbf-2 double mutant suggesting that LST-1 and SYGL-1 act with, or in parallel to, FBFs to function ( Further research will be required to determine if SYGL-1 and LST-1 are required to selectively target different FBF mRNA targets, or if they assist in regulating similar targets as is suggested based on the increase in GLD-1 levels in both lst-1 and sygl-1 mutants (Table 1)