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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Wong C.K., McLean B.A., Baggio L.L., Koehler J.A., Hammoud R., Rittig N., Yabut J.M., Seeley R.J., Brown T.J., Drucker D.J

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(3) Clinical Gaps : While preclinical data (e.g., berberines 500 mg/kg dose in rats) are promising, human trials are sparse, with only cinnamon, coffee, and wheat fiber tested in modest cohorts