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6 Wnt/-catenin signalling is essential to maintain the undifferentiated state of the stem cell population in the intestinal epithelium 234,235,236,237,238 Abnormal activation of the Wnt/-catenin pathway by mutations in adenomatous polyposis coli, AXIN2, or -catenin (CTNNB1) is responsible for the initiation of almost all colon cancers

Theyre incredibly useful because they donate an extra electron to free radicals, neutralising them without becoming unstable themselves

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