Participants were fully informed and agreed to the study through written consent (according to the protocols of the National Ethics Committee for Clinical Studies)
For the chronic dosing studies, most studies are looking at doses of 4 g/day.[ref] (This used to be the maximum recommended acetaminophen dose per day, but that has now changed to 3g/day.) For reference, a single over-the-counter Extra Strength Tylenol is 500 mg, with the directions saying not to exceed 6 tablets in 24 hours (so 3g/day)
Not meant to replace topical skincare or dermatology
Citrulline supplementation improves microvascular function and muscle strength in middle-aged and older adults with type 2 diabetes
Ahishali E, Demir K, Ahishali B, Akyuz F, Pinarbasi B, Poturoglu S, Ibrisim D, Gulluoglu M, Ozdil S, Besisik F, Kaymakoglu S, Boztas G, Cakaloglu Y, Mungan Z, Canberk Y, Okten A (2010) Electron microscopic findings in non-alcoholic fatty liver disease: is there a difference between hepatosteatosis and steatohepatitis
Cell Host Microbe 31, 712733