Biomarkers of health effects PMI researchers reported a controlled clinical study that applied systems pharmacology and showed that exposure-response gene signature in blood was similarly reduced in smoking cessation or switching to IQOS groups compared to continued smoking 98
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Downregulated DEGs in ionocytes and PNECs were enriched in defining markers of these cells, suggesting a loss of their specialized function in smokers (Fig
"Maternal exposure to air pollution and risk of autism in children: A systematic review and meta-analysis"
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When inhaled, these harmful chemicals can lead to both short-term and long-term health problems, from emphysema to heart disease
