The National Institute for Health and Care Excellence (NICE) in the United Kingdom provided recommendations in March 2023 to use semaglutide (2.4 mg once a week) in adults with a body mass index (BM) of 35 kg/m 2 or more, or BM 30 kg/m 2 or more with comorbidities and enrolled on a specialist Tier 3 weight management program (NICE, 2022) 28
Epithalon may potentially preserve the DNA from damage by activating the telomerase and decreasing the number of errors in the DNA strands
There were no significant differences between the two groups in terms of sex, ethnicity, marital status, living arrangement, level of education, and employment status and also medical history (with an exception of vision problem), as shown in Table 1
Autoimmune considerations : There is no evidence that GLP-1 receptor agonists worsen autoimmune thyroid disease or trigger new-onset Hashimoto's thyroiditis
Supporting Research on Semaglutide Clinical trials have shown that semaglutide can lead to significant weight loss and improved glycemic control
Apart from the increased thyroid hormones, clinical studies have found that decreased level of TSH is an important risk factor for depression in the elderly (112), although its underlying mechanism remains unknown
