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They are used only within a physician-supervised program with proper evaluation and monitoring

Dysfunctions in MTHFR can lead to elevated homocysteine levels, increasing the risk of health issues like heart disease, cancer, and stroke

Future clinical development should focus on biomarker-guided patient selection and the development of formulations that ensure consistent bioavailability to maximize therapeutic efficacy

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Drug design, development and therapy 8:20692074 Gurel A, Armutcu F, Sahin S, Sogut S, Ozyurt H, Gulec M, Kutlu NO, Akyol O (2004) Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys

Finally, melatonin decreased HPSC viability in a time and concentration-dependent manner