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The presence of multiple intracellular signaling systems suggests potential plasticity in GLP-1 action and supports the hypothesis that selective engagement of GLP-1R could preferentially recruit beneficial signaling pathways

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Other strategies focus on optimizing mitochondrial function, as they are the main source of energy production (adenosine triphosphate, ATP) within the cell

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R., Liu, W., Xing, F., Fukuda, K