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The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms

hold a published patent (WO/2023/180570) that covers the in vitro method for identifying anti-senescence compounds based on detecting the binding of said compound in the presence of at least one phosphorylated amino acid in the transcription activation domain (TAD) domain of mammalian protein p53

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Nature 266:565567 Xu D, Trmulot L, Yang Z, Mhamdi A, Chtel-Innocenti G, Mathieu M, Espinasse C, Van Breusegem F, Vanacker H, Issakidis-Bourguet E, Noctor G (2025) Cytosolic monodehydroascorbate reductase 2 promotes oxidative stress signaling in Arabidopsis

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& Hosseinzadeh, H