The medication has demonstrated significant efficacy in clinical trials, with patients achieving meaningful reductions in hemoglobin A1c levels and body weight
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For a full overview of what retatrutide is, how it works, and what the trials show, see our complete retatrutide guide
1 The study details 800 participants in the interim analysis (1,197 total enrolled) with biopsy-confirmed MASH and moderate to severe fibrosis (stage F2 or F3) Participants were randomly assigned to receive semaglutide 2.4 mg weekly or placebo Treatment lasted 72 weeks 2:1 randomisation (534 semaglutide, 266 placebo) Resolution of MASH (primary outcome) Fibrosis improvement (primary outcome) Combined outcomes About a third (32.7%) of participants taking semaglutide achieved both MASH resolution and fibrosis improvement, compared to 16.1% on placebo
Muscle Cramps: These can be caused by electrolyte imbalances, so make sure to maintain your intake of sodium, potassium, and magnesium
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