3.4 Limitations of stimuli-responsive nanoparticle designs Stimuli-responsive NP systems, including those triggered by pH, enzymatic activity, or ROS, depend on pathological thresholds that vary widely among patients, disease locations, and inflammatory states (Barros et al., 2026)
Moreover, there are specialized cells that include: Endothelial cells play a role in forming new blood vessels (angiogenesis) to support the growth of new developing tissue
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