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A meta-analysis that included five randomized controlled trials found that NAC reduced the duration of intensive care needs in patients with ARDS
An RCT in 72 patients with NAFLD found that NAC (600 mg twice daily) for 3 months significantly improved liver enzymes (ALT, AST) and markers of oxidative stress compared to control, though it did not significantly improve liver histology on biopsy (Khoshbaten et al., Hepat Mon, 2010) [33]
Therefore, when we intend to do an experiment to study ECD using cell culture, the source of the cells and the type of in vitro model to be used must be well planned since there are various options available (Fig
10.1136/gutjnl-2024-333378 81 VirtueA
As discussed, Glutathione is extremely well tolerated when given intravenously in our experience it has an almost non-existent incidence of side effects
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