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Mutations of -catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors

Eur J Biochem 269, 24142420

[21] When treated with cyanocobalamin, patients with Leber's disease may develop serious optic atrophy, possibly leading to blindness, based on few case reports

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This same technique promotes melanocyte activity and aids in localized repigmentation, and it is commonly used in conjunction with topical treatments

For example, those with more severe deficiencies or certain health issues might need different doses