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Another study used Radix Rehmanniae Praeparata (400 mg, p.o., for 21 days) in AD mice aged 68 weeks, which resulted in decreased expression of pSer404-tau protein but increased expression of insulin receptor (INSR) and IRS-1 proteins in the hippocampus and cortex of RRP-treated animals

28,29 Similarly, methylation or mutation of rRNA can confer resistance to macrolides, lincosamides, or tetracyclines

ClinicalTrials.gov

Fernndez L, Castro I, Arroyo R, Alba C, Beltrn D, Rodrguez JM