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This results in substantially higher free peptide bioavailability at the muscle IGF-1R compared to equimolar native IGF-1 in serum-containing research systems an important consideration for in vitro experimental design where IGFBP concentrations vary by medium formulation and serum lot

Avoids injection-related discomfort

The project was directed by MR and HFN who also wrote the manuscript

10.1016/j.exer.2020.107922 Exp Eye Res

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It is commonly examined in experimental settings focused on receptor-specific activity, peptide behavior, and analytical assay applications