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By measuring the transcriptome and metabolome of the LDH1 knockout strain ( ldh1 ) under LA stress and comparing it with the wild-type strain BY4741, we found that under the condition of LDH1 knockout, the accumulation of NAD + intermediates would be activated, disrupting normal cell functions and causing cell damage

the second step, which adds the glycine residue, is catalyzed by glutathione synthetase (GS)

Mantri S, Lepore M, Edison B, Daeschler M, Kopil C, Marras C, et al

(2020) 8:e00679

Cancer may potentially be treated by using avocado components