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A 2021 review covering 30 years of clinical data described cerebrolysin as demonstrating "a disease-modifying effect by slowing down the progression" of Alzheimer disease, but this language outpaces what the clinical trial designs can definitively prove

Incretin hormones, such as GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), are involved in several functions such as regulating glucose levels, delaying gastric emptying, and reducing food intake [16, 17]

Phentermine carries a higher risk of dependency and tolerance, while GLP-1 medications maintain consistent effectiveness when dosed appropriately

Neurol Sci 38(7):11671186

This is a general theme in space: often, we don't find a lot of GLP-1R in places that we know are affected

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